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Its precise mechanism of action is unknown. CB1 is predominantly distributed in the central nervous system, while CB2 is localised predominantly in immune cells. THC is a partial agonist at CB1 receptors and can behave as either an agonist or antagonist at CB2. CBD is an agonist of the TRPV -1 (vanilloid) receptor. Further information The Product Monograph is available to health care professionals upon request. For medical enquiries regarding SATIVEX, please contact the medical in.
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